Jakob Troidl

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I am an AI Scientist at HHMI Janelia Research Campus, affiliated with the AI@HHMI initiative. I lead the MIA-AI project, which develops foundational datasets and models for microscopy image analysis, integrating self-supervised pre-training, multi-modal learning, and cross-scale reasoning in biological systems.

I hold a Ph.D. in Computer Science from Harvard University, advised by Hanspeter Pfister. During my PhD, I was as a visiting researcher in the Turaga Lab at HHMI Janelia and a Machine Learning Fellow at E11.bio. I received my M.Sc. and B.Sc. degrees in Computer Science from TU Wien, Austria, and am originally from Regensburg, Germany.

My research spans applied machine learning and data visualization, with a particular emphasis on connectomics. My work centers on the development of scalable, interactive visual analysis systems and representation learning methods for uncovering the structural organization of the brain.

news

Mar 04, 2026 💬 I’ll attend the AI and Biology conference at EMBL and the Synapses at Scale workshop at COSYNE.
Mar 04, 2026 📖 My PhD thesis Scaling Computational Connectomics is now available online.
Jan 26, 2026 📢 I started as an AI Scientist at HHMI’s Janelia Research Campus.
Nov 18, 2025 🎓 I defended my PhD. Here’s the recording.
Jul 25, 2025 📢 Three papers accepted to IEEE VIS 2025 and one paper accepted to MICCAI EMA!
Jun 06, 2025 💬 I presented our preprint on neuron shape reasoning at the Modeling and Analysis of Connectomes conference and at the Frontiers in NeuroAI symposium.
Apr 10, 2025 💬 CAVE is out in Nature Methods. Check the paper out here.
Mar 14, 2025 💬 I will join E11.bio this summer as a ML fellow to work on automated connectome proofreading.
Dec 21, 2024 💬 I gave a talk on automated connectome proofreading at E11.bio, TU Wien and Google Research.

selected publications

  1. momo.png
    MoMo-Combining Neuron Morphology and Connectivity for Interactive Motif Analysis in Connectomes
    Michael Fekadu Shewarega* , Jakob Troidl*, Oliver Alvarado Rodriguez , and 6 more authors
    IEEE Transactions on Visualization on Computer Graphics , 2025
  2. gnsr.png
    Global Neuron Shape Reasoning with Point Affinity Transformers
    Jakob Troidl, Johannes Knittel , Wanhua Li , and 3 more authors
    bioarxiv, 2025
  3. niiv.png
    niiv: Interactive Self-supervised Neural Implicit Isotropic Volume Reconstruction
    Jakob Troidl, Yiqing Liang , Johanna Beyer , and 5 more authors
    MICCAI Workshop on Efficient Medical AI, 2025
  4. h01.jpeg
    A petavoxel fragment of human cerebral cortex reconstructed at nanoscale resolution
    Alexander Shapson-Coe , Michał Januszewski , Daniel R. Berger , and 28 more authors
    Science, 2024
  5. vimo-teaser-02.png
    Vimo: Visual Analysis of Neuronal Connectivity Motifs
    Jakob Troidl, Simon Warchol , Jinhan Choi , and 8 more authors
    IEEE Transactions on Visualization and Computer Graphics (IEEE VIS), 2023